A study of more than 80,000 people with type 2 diabetes found that those who stopped taking GLP-1 drugs had nearly twice the rate of heart attacks, strokes and death compared with those who kept taking them. So the weight-loss shot might come with a rather expensive catch. Once you start, you may not want to stop.
Once you start, you should not stop GLP-1 https://t.co/ZYENBBMtvU
— Neil Floch MD (@NeilFlochMD) November 10, 2026
There are caveats. The study doesn’t prove stopping the medication caused the higher death and heart attack rates, and it didn’t study the general population taking Ozempic or Wegovy just to lose weight. But it’s another reminder that these drugs aren’t necessarily a short-term fix. People lose weight, stop taking the medication, and often regain it. Now researchers are looking at what happens to their cardiovascular health, too.
https://doi.org/10.1016/j.lanepe.2026.101881
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