Tromethamine Side Effects:
Side effects include:
Adverse effects may include respiratory depression, local irritation, tissue inflammation, injection site infection, febrile response, chemical phlebitis, venospasm, hypervolemia, IV thrombosis, extravasation (with possible necrosis and sloughing of tissues), transient decreases in blood glucose concentrations, hypoglycemia, and hepatocellular necrosis with infusion via low-lying umbilical venous catheters.
KETOROLAC TROMETHAMINE- ketorolac tromethamine injection, solution
What is the most important information I should know about medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)?
NSAIDs can cause serious side effects, including:
Increased risk of a heart attack or stroke that can lead to death.
Ketorolac tromethamine is not indicated for use in pediatric patients. The safety and effectiveness of ketorolac tromethamine in pediatric patients below the age of 17 years have not been established.
Sandra Fryhofer, MD, chair-elect, AMA Board of Trustees; AMA’s liaison to the Advisory Committee on Immunization Practices
“The kiddy version contains Tris, which is short for tromethamine, as the buffer. PBS, phosphate-buffered saline, is the buffer used for adults. Extra salt, both sodium chloride and potassium chloride, have been removed in the version for kids. These minor changes make the vaccine product more stable at regular refrigerator temperatures for longer periods of time. The kid version vials can be stored unopened in regular refrigerators for up to 10 weeks.”
h/t Anon Braveheart
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