- Pfizer’s top scientist said it chose a relatively low COVID-19 vaccine dose to minimize side effects.
- Pfizer’s vaccine has 30 micrograms of mRNA, the active ingredient. Moderna’s has 100 micrograms.
- Both vaccines produce similar side effects, according to the CDC.
Pfizer’s top scientist defended the dose of the active ingredient in the company’s COVID-19 vaccine, which is lower than in Moderna’s vaccine.
Pfizer’s COVID-19 vaccine has 30 micrograms of mRNA, while Moderna’s has 100 micrograms. Scientists have speculated that this could be a reason Pfizer’s shot produced a lower antibody response than Moderna’s in recent studies.
Philip Dormitzer, Pfizer’s chief scientific officer, told the Financial Times on Wednesday that Pfizer and its codeveloper BioNTech “used the minimum dose level” to get an immune response that was stronger than catching COVID-19.
Dormitzer added that a higher dose might have risked more side effects.