BILL GATES: Biggest fears about what’s coming next… ‘Disease X’

The seat of power in Bill Gates’s empire occupies the top floor of an anonymous suburban office block overlooking Seattle’s Lake Washington. Here, in the inner orbit of the second richest man on earth, everything – down to the modern artwork and screens embedded into the walls, to the gleaming staff canteen replete with a faux wood-burning stove – is curated to the utmost precision.

No more so than the man himself, whose daily schedule is managed by assistants into five-minute chunks. When Gates arrives for our interview in his glass office, nicknamed “The Fishbowl”, he cuts an immaculate presence, tall and surprisingly suave in dark trousers and slate grey cashmere. The only blot is a marker pen smudge running the length of his left palm, presumably from scrubbing furiously at some white board earlier that day. Even in the 62-year-old Microsoft founder’s second life as the world’s philanthropist-in-chief, the old number-cruncher dies hard.

So, too, the ability to always keep one eye on the future. When I ask which challenges to global health security he fears the most, Gates outlines three: antibiotic resistance, cuts to government funding to improve health in the world’s poorest countries, and the next unknown disease, referred to by the World Health Organisation simply as ‘Disease X’.

“We are not fully prepared for the next global pandemic,” he says. “The threat of the unknown pathogen – highly-contagious, lethal, fast-moving – is real. It could be a mutated flu strain or something else entirely. The Swine Flu and 2014 Ebola outbreaks underscored the threat.”

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