“Researchers at the Mayo Clinic have all but ruled out vitamin E oil and other thickeners as the possible culprit in a wave of vaping-related illnesses and deaths, deepening the mystery of what might be at fault.
Instead, the clinic pathology team reported in the New England Journal of Medicine on Wednesday that the lung tissue they examined suggests the damage was more likely caused by inhaling a caustic chemical fume.
. . .
In the new study Wednesday, Dr. Larsen and his colleagues examined lung-biopsy tissue from 17 patients at hospitals around the country, all of whom had been diagnosed with vaping-associated lung injuries. Almost three-quarters of them had vaped using cartridges containing marijuana or cannabis oils, the pathologists said. Two of them died.
. . .
But the Mayo Clinic’s lung-tissue samples, the first to be examined directly under a microscope, showed no sign of oils. “We have not seen any evidence of that in any of our cases,” Dr. Larsen said.”
Listen, I know this is a hot topic here on GLP and many are going to get angry over the headline here. But, let’s be honest here. I don’t think it’s wise to jump on the Vitamin E bandwagon right now until there is definitive, absolute proof that this is what the culprit is. As much as everyone wants it to be this, I don’t think it’s wise for people to push that this is the problem when it is still not known if this is the problem.
And before anyone wants to go calling me a big tobacco shill, I was vaping all the way up until the first death occurred here in Kansas. I personally stopped vaping that very night because I have done the respiratory failure last December and it’s not fun and I don’t want to go there again. To be quite frank, I was scared out of my wits.
I personally will not start vaping again until it has been figured out for sure what is going on here. I want to personally be sure that it’s not a flavoring agent or something like that. I don’t want to see anyone else come down with this because they thought they were 100% safe because everyone said it’s the Vitamin E thing, when in all honesty, we don’t know for sure that it is.
Also, I didn’t mention it in my first post, but I know at least in Kansas, it is being reported that some of the injuries are from nicotine only. So, that is also my reason for my caution on vaping.
Vaping lung injuries resemble chemical burns, expert calls it the ‘tip of the iceberg’
As the Centers for Disease Control and Prevention (CDC) continues to investigate a spike in vaping-related injuries, a new breakthrough study from the New England Journal of Medicine is providing evidence that toxic chemicals may be to blame.
. . .
Others have implicated THC, the psychoactive ingredient in cannabis, after reports that the majority of those with the illness used a vape containing it. But with others saying they only used nicotine, no single ingredient or product can be cited as the cause.
. . .
The biopsies showed no signs that a buildup of oil in the lungs was to blame. Instead, the images resembled those of individuals who had been exposed to toxic chemicals — suggesting that there may be other, as-of-now unidentified contaminants at play.
‘While we can’t discount the potential role of lipids [oils], we have not seen anything to suggest this is a problem caused by lipid accumulation in the lungs,’ Brandon Larsen, MD, PhD, a surgical pathologist at Mayo Clinic in Arizona and one of the lead researchers wrote in the study. ‘Instead, it seems to be some kind of direct chemical injury, similar to what one might see with exposures to toxic chemical fumes, poisonous gases and toxic agents.’”
And another study is linking it to a chemical used to fuse the metal in the pens.
Colorado Lab Results Point to New Culprit in Vaping Cases: A Specific Chemical Used in Cheap Vape Pens
“A new study by a Colorado lab points to a new potential culprit in the nationwide wave of lung injuries caused by vaping: a rare disease caused by inhalation of a chemical present in many cheap vape pens that is used to fuse metals together.
The study used data from 53 patient cases in Wisconsin and Illinois who suffered severe lung illness due to vaping. From that study, the lab concluded that the vaping illness symptoms directly correlate to an advanced stage of a very rare disease, almost exclusively suffered by welders and others who inhale chemical concoctions, called Metal Fume Fever.
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The study out of the Colorado lab largely backs up the findings out of the Mayo Clinic’s study of 17 lung tissue samples last week, which found that all the injuries resembled severe chemical burns, similar to those caused by mustard gas, a biological weapon created during World War I.”