Scientists in Israel showed they could turn back the clock in two key areas of the body believed to be responsible for the frailty and ill-health that comes with growing older. As people age, the protective caps at the ends of chromosomes – called telomeres – shorten, causing DNA to become damaged and cells to stop replicating. At the same time, senescent cells build up in the body, preventing regeneration.
Now scientists have shown that giving pure oxygen to older people while in a hyperbaric chamber increased the length of their telomeres by 20%,a feat that has never been achieved before. The growth may mean that the telomeres of trial participants were now as long as they had been 25 years earlier. The therapy also reduced senescent cells by up to 37%, making way for new healthy cells to regrow. Animal studies have shown that removing senescent cells extends remaining life by more than one third.