All clinical trials of pharmaceutical products should be pre-registered, and the results should always be released. The prevalence of deliberate non-disclosure means that data which shows adverse side-effects is simply being swept under the carpet.
The World Health Organization (WHO) has warned that failing to report results can lead to the use of “suboptimal or even harmful products”.
The criteria of the scientific process are not fulfilled if “unhelpful” data is not released. It’s quite literally, pseudo-science: going through the motions until you get the results you want.
Some of the UK’s top universities are failing to disclose the results of clinical trials, with experts warning that these unreported studies leave an incomplete and potentially misleading picture of the risks and benefits of treatments.
Previous research has found that around half of all trials go unreported, particularly those whose results are negative. And the World Health Organization (WHO) has warned that failing to report results can lead to the use of “suboptimal or even harmful products”.
Now, a report from pressure group Transparimed has found that UK universities have failed to publish the results of 1,671 clinical trials listed on both European and United States trial registries. And 19 out of the 27 UK universities studied have failed to upload a single missing trial over the past two months.
The report says that unless universities post the results of these trials soon, valuable medical research data will be lost forever. Failing to publish will also lead to duplication of research, much of which is publicly funded, the report warns.
Since 2014 there has been a European Union requirement for all clinical trials conducted by member states to be reported and registered, although there are no sanctions for institutions which fail to comply.
In 2015 the WHO published standards on clinical trials, saying that the registration and reporting of all trials was a “scientific, ethical, and moral responsibility”.
The Transparimed report says that the 27 universities covered by this report have posted summary results for only 11 per cent of their trials.