Novartis, Incyte to testruxolitinib for use in Covid-19 associated cytokine storm

by TurquoiseRose

www.pharmatimes.com/news/novartis,_incyte_to_test_jakavi_for_coronavirus-linked_cytokine_storm_1335533

Novartis and Incyte are planning to launch a clinical study to test the potential of Jakavi (ruxolitinib) in patients with COVID-19 associated cytokine storm, a type of severe immune overreaction that can result from the infection and may contribute to respiratory compromise in some patients.

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According to the Swiss drugmaker, preclinical and preliminary clinical evidence suggests that the JAK inhibitor could reduce the number of patients requiring intensive care and mechanical ventilation.

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Phase III Trial

www.targetedonc.com/news/phase-iii-trial-planned-for-ruxolitinib-to-treat-covid19related-cytokine-storm

Research referenced in the above article.

COVID-19: consider cytokine storm syndromes and immunosuppression

Cytokine storm

www.ncbi.nlm.nih.gov/pmc/articles/PMC3294426/

 

 

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